The most critical portion of a science is the lab portion. That's where you should develop scientific thinking skills and an understanding of the nature of science. Yet, hands-on labs aren't doing the job due to expense, time, and incorrect design.
Build online science lab investigation experiences using real videoed experiments with highly interactive software that allows students to take individual data using their own care and judgment. Add on all of the features that modern pedagogy suggests. Note that simulations cannot be authentic.
Now, you can have students do their labs at home or in the library or even at a coffee shop. This approach really does engage students. It really does improve science comprehension. It really does fill a void in science education inexpensively and efficiently.
One implementation can be found at smartscience.net.